সোমবার, ৩১ অক্টোবর, ২০১১

Plane crashes into Tijuana car shop, killing 3 (AP)

TIJUANA, Mexico ? Mexican authorities say a light airplane taking off from the border city of Tijuana has crashed into an auto repair shop near a street market, killing three people and setting fire to several cars.

Baja California state agent Andre Cato says the 62-year-old pilot and his 17-year-old daughter died when the plane smashed into repair shop near the airport Monday. An explosion killed a 40-year-old man who had taken his car for repairs.

At least eight cars burned at the repair shop, which is in a neighborhood close to the international border with San Diego, California.

Authorities are investigating what caused the accident.

Source: http://us.rd.yahoo.com/dailynews/rss/latam/*http%3A//news.yahoo.com/s/ap/20111031/ap_on_re_la_am_ca/lt_mexico_tijuana_plane_crash

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Rare October snowstorm pelts Northeast (Reuters)

BOSTON (Reuters) ? A rare October snowstorm bore down on the heavily populated Northeast on Saturday, with some areas bracing for up to a foot of snow and major power outages.

In Pennsylvania, Maryland and West Virginia, more than 44,000 customers were without power, the utility Allegheny Power said. Hour-long flight delays were reported at Philadelphia International Airport.

The snow threatened traffic problems for 100,000 college football fans at a game in State College, Pennsylvania between Penn State and the University of Illinois.

By midday, there were a few flakes in parts of New Jersey and New York.

"It's a strong storm for October," said AccuWeather.com senior meteorologist Paul Walker. "We don't usually see storms this deep and this strong."

While October snow is not unprecedented, this storm -- starting as rain and changing to snow as temperatures drop -- could set records.

Hartford, Connecticut, Allentown, Pennsylvania, and Worcester, Massachusetts were among the cities that could get up to a foot of snow, forecasters said.

Allentown typically sees its first measurable snow around December 5, The Weather Channel said. Boston generally sees snow around the end of November, while New York City and Philadelphia usually get their first flakes in mid-December.

Major coastal cities are not likely to be spared by this weekend's storm, meteorologists said.

New York could see four inches of snow, tapering off on Saturday night, The Weather Channel said. In Boston, afternoon rain will turn to snow overnight, bringing up to three inches.

Source: http://us.rd.yahoo.com/dailynews/rss/us/*http%3A//news.yahoo.com/s/nm/20111029/us_nm/us_weather_northeast

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The most helpful way to create electricity from the sun, when you just can't pay for to employ the professionals, would be with a photo voltaic panel kit.

Source: http://www.oneview.com/url/25499841/

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How Emerging Economies are Altering the World's Flow of Goods (Time.com)

For decades, the Chinese town of Manzhouli, perched on the desolate border with Russia, was frozen in a remote corner of the Cold War. As an ideological schism between the two Communist giants escalated into a full-blown conflict ? bloody clashes erupted along their 4,300-km border in 1969 ? the poor residents of Manzhouli had little contact with their Russian neighbors huddled in the Siberian cold only a few steps away. A mere trickle of state-sponsored trade passed through the heavily fortified border, leaving Manzhouli's citizens dependent on a local coal mine for jobs.

Today, however, Manzhouli is a testament to the wealth that can be created by connecting the world's great emerging economies. As relations thawed between Moscow and Beijing after the 1991 collapse of the Soviet Union, the border opened, private businessmen jumped into importing and exporting, and the fortunes of the two communities merged. Trade between Russia and China reached $55 billion in 2010, seven times more than in 2000. Timber and oil flow into resource-hungry China, while China's roaring factories ship machinery, textiles and other manufactured goods back in return. About $9.8 billion of goods passed through tiny Manzhouli in 2010, more than twice the amount just five years earlier. In downtown Manzhouli, Russian tourists troll for cheap Chinese-made boots and winter coats in shopping arcades, where the signs are in Cyrillic and the official haggling language is Russian. With money to be made, Manzhouli became a magnet for northern China's eager and entrepreneurial. The town's population has surged by a factor of 15 since the end of the Cold War, to 300,000. "Before, trade was zero, but now it is booming, and people's quality of life has benefited," says Li Yongsheng, a manager at the Manzhouli Border Economic Cooperation Zone, an industrial park founded by the government to foster business with Russia. "The old hostilities are basically gone." (See "Global Economy: Was the Past Decade So Bad?")

Manzhouli's success story is being re-created again and again across the emerging world. Flows of goods, people and capital among major developing economies are becoming a larger and larger source of exports, jobs, financing and economic growth for these up-and-coming nations. The trend ? a move away from trade and investment flows dominated by Western consumer demand ? could reshape the world economy. Tightening economic ties within the emerging world can provide a badly needed boost for a global economy still searching for a route out of the Great Recession ? the primary concern of November's Asia-Pacific Economic Cooperation (APEC) summit in Hawaii. The growing linkages are redirecting patterns of investment, trade and migration, altering the role of the U.S. in the global economy, redrawing political alliances and sparking new geopolitical rivalries. And we're just at the very beginning of this history-altering process. Stephen King, chief economist at banking giant HSBC, figures that trade and capital flows between emerging regions of the world ? Asia, Africa, the Middle East and Latin America ? could increase tenfold over the next 40 years. He calls these new connections "a 21st century version of the original Asian Silk Road" that is "set to revolutionize the global economy."

The signs are apparent everywhere. China, not the U.S., has become India's largest trading partner, with the exchange between the two countries surging 28-fold over the past decade to almost $62 billion in 2010. When Chinese Premier Wen Jiabao visited New Delhi last December, the two sides inked $16 billion in trade and financing deals; when U.S. President Barack Obama journeyed to India a month earlier, he managed only $10 billion. India and Brazil already export more to fellow emerging markets than to the developed world. China is the largest foreign investor in Brazil, challenging the historical dominance of the U.S. in Latin America, while a $3.1 billion investment by Chinese oil company CNOOC in Argentine energy firm Bridas was the biggest acquisition in Argentina in 2010. Last year, Russia's Rusal, the world's largest aluminum producer, chose to launch its initial public offering not in London or New York City but on the Hong Kong Stock Exchange, becoming the first Russian firm to do so. (See photos of Chinese investment in Africa.)

The New World Trading Order
The burgeoning trade and investment among emerging countries is a dramatic shift in how the world economy has worked for several centuries. Traditionally, trade has flowed between "North" and "South" ? the developed and developing worlds. Natural resources, from spices to cotton, were shipped into the industrialized West, which in return exported textiles and other factory-made goods. After World War II, this system became more complex, thanks to improved transport and communications. Asian upstarts like South Korea and Singapore grew rich off of outsourcing. Their plentiful, cheap labor assembled clothes, shoes and electronics, often with design and technology from the West, then shipped the goods to Walmarts for U.S. consumers. With shoppers in places like India and Indonesia still poor, there was little incentive to reach out to them. Tense relations between developing nations ? such as the border conflict between Russia and China that paralyzed Manzhouli ? often created more hurdles. The U.S. and Europe dominated the world's trade and capital, and everyone depended on them for growth and jobs.

See TIME special report "World Economic Forum: Davos 2010."

That pattern began to change after China jumped into the globalization game in the 1980s. Factories in Shenzhen and Shanghai became the centerpieces of "borderless-manufacturing" networks in which parts for TVs, mobile phones and other goods were produced across Asia, then shipped to China for final assembly, spurring greater trade within the region. As rapid growth in China, India and other emerging markets turbocharged local incomes, they became export destinations in their own right, with fellow emerging-nation companies selling to one another's consumers. The connections continue to draw in more and more parts of the emerging world. Trade between the developing economies of Asia and Latin America, for example, grew sevenfold over the 10 years ending in 2010, to $268 billion. China and India, seeking access to raw materials and new customers, have become patrons of Africa. Trade between India and Africa has exploded from a mere $1 billion in 2001 to $50 billion in 2010. Last year, Indian telecom-service provider Bharti Airtel acquired operations in 15 nations in sub-Saharan Africa for $10.7 billion in one of the biggest cross-border deals in Indian history. Ganeshan Wignaraja, a specialist in economic integration at the Asian Development Bank (ADB) in Manila, says these emerging-market ties are creating a "third pillar" of growth within the world economy, alongside the U.S. and the E.U. "We're heading toward a multipolar world," he says.

The consequences of that go well beyond the mere movement of goods. The more important trade and investment within the emerging world become, the less important the West becomes to the global economy, a trend accelerated by the Great Recession. While the economies of the West sag under high debt and joblessness, China, India and much of the rest of the emerging world have powered through the downturn and are looking more and more to one another. And as the major emerging economies grow closer economically, they are discovering shared political interests. The BRICs ? Brazil, Russia, India and China ? have already started to hold regular summits to coordinate their efforts on major issues like reforming the global financial system. (South Africa joined the latest conference as well.) They are also challenging the established economic order. China and Russia, for example, have led a charge to replace the U.S. dollar as the world's No. 1 reserve currency. If the supersonic trade and investment among emerging economies continues, "the importance of the U.S. and Europe economically and politically would diminish," says HSBC's King. (Read about corruption and abuse of Power threatening Russia's economic gains.)

Corporate executives are discovering new opportunities in their emerging compatriots as well. Companies that might not have broken into developed markets with little-known brand names have found success in emerging markets, where loyalties aren't as fixed. Chinese mobile-phone maker G'Five saw its sales in India surge more than 75% in the past fiscal year; its trendy phones appeal to Indian consumers with thin wallets. Chery, a major Chinese carmaker, would likely struggle in the competitive U.S. market, where Chinese-made goods suffer from a reputation for shoddy quality. Instead, Chery has invested in emerging economies and has 16 factories either operating or under construction in countries such as Russia, Egypt, Iran, Indonesia and Brazil. Chinese PC maker Lenovo decided in 2009 to focus more on emerging economies, believing its experience at home could give it an advantage in other developing nations. In India, for instance, the firm replicated sales techniques that worked in poor areas of China, like showing free movies to villagers as part of PC-marketing road shows. The strategy has paid off. Revenue in emerging markets (excluding Lenovo's Chinese base) ballooned 46.5% in the quarter ending in June, compared with only an 8.5% increase in developed countries, helping the company gain PC market share globally.

Building Bridges (Literally)
The continued integration of the emerging world is far from assured. Developing countries have higher tariffs and stiffer restrictions on capital flow than developed ones. Roads and transport networks have been designed to deliver goods to the U.S. and Europe, not from one developing country to another, often making the shipping of products slow and expensive. As a result, the flow of trade and money is still small compared with that between North and South. Despite its eye-popping growth, trade between India and China amounts to a mere sixth of that between China and the U.S. Persistent political tensions could also flare up and impede economic relations in the future. China and India, for example, still spar over unresolved border disputes, while New Delhi's support for the Dalai Lama irks leaders in Beijing who consider him a dangerous separatist.

See "India vs. China: Whose Economy Is Better?"

In Manzhouli, there is a gap between the potential of the Russian trade and the reality. The markets at a tourist zone outside town, where Russians can shop without visas for Chinese-made wares, are almost completely shut by 1 p.m. A giant hotel not far from the airport, topped by Russian-style maroon domes, appears abandoned. Chinese officials complain that their Russian counterparts hamper progress by erratically changing regulations and trade policies. "The Russian bureaucrats are not eager to move forward with economic development," says Li of the Manzhouli economic zone. "Chinese officials are willing to sacrifice their holidays for development. Russian officials never work overtime." There are physical impediments as well. The gauges of the Russian and Chinese railways are different, forcing trade goods to be transferred between trains at the Manzhouli border ? a productivity-killing process.

Active efforts are under way to dismantle these barriers. Developing Asian and Latin American countries have completed 13 free-trade agreements since 2004. Russian Prime Minister Vladimir Putin recently raised the idea of forging a free-trade "Eurasian Union" among former Soviet states, and during an October visit by Putin to Beijing, Russia and China formed a joint $4 billion fund to encourage investment between them. New roads, railways and ports are connecting emerging nations more than ever before. Burma is rebuilding an old road across the country that will link China and India, potentially cutting the cost of transporting goods between them by some 30%. Beijing, wary of relying on the Panama Canal for the shipping of Brazil's vital natural resources, is proposing a new route through Colombia, with a $7.6 billion railway connecting its Pacific and Caribbean coasts. And China is liberalizing (albeit slowly) its currency regime, encouraging its major partners to use the renminbi instead of the dollar in their trade. HSBC figures that the renminbi could be the currency of choice in at least half of China's trade with other emerging nations in three to five years. (See photos of China's high-speed rail.)

But even as some roadblocks come down, others go up. Competition among major emerging markets for exports, investment, jobs and global influence fuels tensions. Officials in Brazil and India have complained that China's control of the renminbi's value hampers their exports by keeping competing Chinese goods artificially cheap. Resentment toward China spans from Brazil to Zambia over Chinese investors' buying up large swaths of their economies while providing few benefits in return. Resolving such differences could be crucial for the future of the emerging world. As HSBC's King points out, giant emerging economies can no longer count on the overextended U.S. consumer to raise their living standards up to the level of the West; only exports and growth created within the emerging world can achieve that. Consulting firm Accenture estimates that India's expanding business with other emerging markets could create 28.2 million jobs in the country by 2020. And as the emerging world becomes more integrated, pressure mounts on the U.S. and Europe to join in ? by, for example, signing more free-trade agreements like the ones Washington approved in October with South Korea, Colombia and Panama. "The story for the developed countries is that you have to get on your bike and be part of the rush to key emerging markets," says ADB's Wignaraja. Otherwise, "you run the risk of being left out."

Huang Jincai has no intention of letting that happen to him. The Manzhouli-based timber processor has pinned all his hopes ? and money ? on China-Russia trade. In 2003, Huang was a migrant worker, spending long hours in the Russian Far East cutting timber. Today, his desk overlooks a buzzing Manzhouli from the 20th floor of an office tower two blocks away from the new, swank Shangri-La Hotel. Over the past seven years, Huang, his brother and a Russian partner have invested almost $5 million in a timber-processing factory in Russia that employs 100 people, and this year he started a Manzhouli company to import and sell the timber. Though he regularly confronts difficulties, from bewildering local tax codes to occasional Russian hostility to Chinese workers, those problems can't squelch his enthusiasm. "My life has changed a lot" because of the Russia trade, Huang, 31, says. "I'm pretty optimistic. After all, the trade just can't stop." No, it can't.

? with reporting by Nilanjana Bhowmick / New Delhi, Jessie Jiang / Manzhouli, Simon Shuster / Moscow And Sheena Rossiter / S?o Paulo

See photos of American colleges in India.

Read "School Is a Right, but Will Indian Girls Be Able to Go?"

View this article on Time.com

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Source: http://us.rd.yahoo.com/dailynews/rss/world/*http%3A//news.yahoo.com/s/time/20111029/wl_time/09171209798600

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Iraqi PM: 615 detained in anti-Baathist sweep

(AP) ? Iraq's prime minister said Saturday that 615 people have been detained in a security sweep targeting members of the former ruling Baath party.

Arrests on this scale are likely to alarm Sunni Arabs, who consider use of the term "Baathists" by Iraq's Shiite-dominated government to be a coded way to refer to Sunni politicians, army officers, and other prominent members of their community.

Sunnis say that Baghdad sometimes uses crackdowns on Baathists as a tool to exert political pressure. The arrests coincide with a recent autonomy push by a mostly-Sunni province in north-central Iraq, the latest bone of contention between Sunni political blocs and the Baghdad government.

Prime Minister Nouri al-Maliki revealed the size of the sweep in comments released Saturday by the state-run Iraqiya TV channel during which he defended the detentions.

He said officials had reason to believe the people arrested were a threat to security but he gave no further details. He did not say when the sweep took place, but a Ministry of Interior statement Thursday said about 500 people had been arrested in recent days.

"The recent arrests, which were carried out by the security forces and were based on information and evidence, were aimed at those who threaten the state security and the state stability. There were 615 detained people," al-Maliki said.

"The Baath Party is prohibited by the Constitution, because it is a criminal party that led to the fall of the national sovereignty and it targeted the Iraqi people through the mass graves, chemical weapons," he said.

The Baath Party ruled Iraq under Saddam Hussein but now is outlawed under Iraqi law, and the prime minister has often accused ex-Baathists of planning terrorist attacks across the country.

Many Sunnis, who were disproportionately represented in the party leadership, feel the attacks against Baathists are a thinly veiled way to go after Sunnis.

A leading Sunni lawmaker, Hamid al-Mutlaq, said the arrests would heighten tensions in Iraq and called the allegations of undermining security "science fiction." He called on the government to move forward instead of arresting people for their past connections to the Baath Party.

"Such acts by the government will anger a lot of people in Anbar, Salahuddin and other Iraqi provinces and this might even threaten the unity of the country and might revive the calls for dividing Iraq," he said, referring to Sunni-majority provinces in western and central Iraq.

"It is the worst time to make these arrests ahead of the U.S. withdrawal," he said.

All American forces are to leave Iraq by the end of this year. Many Sunnis are worried that they will come under increased pressure from the Shiite-led government once the Americans, who they feel have often played a moderating influence, are gone.

De-Baathification, a concept started under the U.S.-led Coalition Provisional Authority which ruled Iraq after the invasion, is an Iraqi government policy of trying to purge important government jobs and positions of former mid- and high-ranking members of the Baath Party. Sunnis have criticized the policy as a way to sideline them from policy decisions and prevent them from ever regaining power.

The prime minister also criticized officials in Salahuddin province, which is a mainly Sunni area north of Baghdad, for a vote they took pushing to establish an autonomous region.

Provincial officials Thursday voted to start the process of creating an autonomous region in Salahuddin, akin to the Kurdish autonomous region in northern Iraq.

Provincial officials and residents have complained that their needs aren't being met by the Shiite-led government in Baghdad and that they could do a better job providing for their own security.

The Iraqi constitution allows provinces to establish autonomous regions but it requires numerous procedural hoops making it unlikely the Salahuddin vote would be anything more than a ceremonial protest.

Al-Maliki said the Baath Party is trying to use Salahuddin province as a "safe haven."

__

Associated Press writer Sameer N. Yacoub contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2011-10-29-ML-Iraq/id-a115df6b27d24fd89a02663094be1383

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রবিবার, ৩০ অক্টোবর, ২০১১

Johnny Depp's 'Rum Diary' Inspired Booze-ography

Today, in theaters around the country, you can pay money to see Johnny Depp get drunk. Real drunk. Blacked-out, forget-who-you-are, hallucination-heavy drunk in "The Rum Diary."
What fun! Who couldn't use a little more drunk Johnny Depp in these uncertain times? With that thought it mind, we started wondering what Depp's other films would look like [...]

Source: http://moviesblog.mtv.com/2011/10/28/johnny-depp-rum-diary-drinks/

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Cain On Top In New Des Moines Register Poll (talking-points-memo)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, RSS and RSS Feed via Feedzilla.

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The Engadget Podcast, live at 5:00PM ET!

Tim and Brian have escaped another Engadget Show mostly unscathed, and now it's time to get back to the wild, unpredictable world of audio podcasting. This time out, they'll be joined by Myriam, direct from Nokia World. Bet you can't guess what they'll be talking about.

Continue reading The Engadget Podcast, live at 5:00PM ET!

The Engadget Podcast, live at 5:00PM ET! originally appeared on Engadget on Thu, 27 Oct 2011 16:41:00 EDT. Please see our terms for use of feeds.

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Source: http://www.engadget.com/2011/10/27/the-engadget-podcast-live-at-5-00pm-et/

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শনিবার, ২৯ অক্টোবর, ২০১১

Europe stocks rise over Europe deal on Greece debt (AP)

PARIS ? European stock markets shot higher Thursday as investors waded into riskier assets, emboldened by EU leaders' pre-dawn agreement to slash Greece's massive debts.

Oil prices rose above $92 per barrel while the euro gained strongly following the European summit dedicated to fixing a debt mess in Greece before it provokes a bigger debt crisis across the continent.

European trading was buoyant from the outset. Britain's FTSE climbed 2.1 percent to 5,670.12. Germany's DAX jumped 3.7 percent to 6,243 and France's CAC-40 gained 3.9 percent to 3,297. Wall Street also headed toward gains, with Dow Jones industrial futures rising 1.6 percent and S&P 500 futures gaining 1.8 percent.

The Greek market rallied on hopes the early morning deal would finally lift the specter of government bankruptcy.

Shortly after opening Thursday, shares on the Athens Stock Exchange were up 3.46 percent at 800.55, with banking stocks up more than 10 percent ? after suffering heavy losses earlier this week.

The hard-fought European deal requires banks to take on 50 percent losses on Greeks bonds. Eurozone countries and the International Monetary Fund will also provide an additional euro100 billion ($140 billion) in rescue loans as a second bailout package for Greece.

EU leaders "stopped the hemorrhaging," said Marc Touati, chief economist at Assya Compagnie Financiere in Paris. "(They) have saved the Eurozone and that's the good news and that's why the markets are reacting positively."

European leaders agreed early Thursday on a plan to provide Greece with more rescue loans to help relieve its crushing debt obligations. It will involve private investors taking bigger losses on the value of their Greek bonds, which would make Greece the first nation that uses the euro currency to be rated in default on its debt.

European Union President Herman Van Rompuy said the deal will reduce Greece's debt to 120 percent of its gross domestic product in 2020. Under current conditions, it would have grown to 180 percent.

In addition, the euro440 billion European Financial Stability Facility will be used to insure part of the losses on the debt of wobbly countries like Italy and Spain, rendering its firepower equivalent to around euro1 trillion ($1.4 trillion).

Loose ends still need to be worked out, and the fundamental problem of low economic growth in the euro zone has not been resolved by the crisis summit, some economists warned.

"(They) have only saved it temporarily," Touati said. "Unfortunately the fundamental problem concerning the absence of growth has not been resolved."

Shares in Asia posted solid gains earlier in the day. Japan's Nikkei 225 index rose 2 percent to close at an eight-week high of 8,926.54. South Korea's Kospi added 1.5 percent to 1,922.04. Hong Kong's Hang Seng gained 3.3 percent to 19,688.70.

Australia's S&P/ASX 200 jumped 2.5 percent to 4,348.20 after trading resumed following a 4-hour technical glitch.

Meanwhile, strong economic reports helped send Wall Street higher on Wednesday.

The Dow Jones industrial average gained 1.4 percent to 11,869.04. The S&P 500 index rose 1.1 percent to 1,242. The Nasdaq composite added 0.5 percent to 2,650.67.

Reports in the U.S. showed businesses ordered more heavy machinery and other long-lasting manufactured goods last month. That indicates businesses are still spending on equipment despite worries about a weak economy and Europe's debt problems. Sales of new homes rose in September after falling for four straight months.

Benchmark crude for December delivery was up $1.98 at $92.15 a barrel in electronic trading on the New York Mercantile Exchange. The contract fell $2.97, or 3.2 percent, to end the day at $90.20 in New York on Wednesday.

Brent crude was up $1.87 at $110.78 a barrel on the ICE Futures Exchange in London.

In currencies, the euro climbed to $1.4003 from $1.3908 late Wednesday in New York. The dollar weakened to 75.83 yen from 76.20 yen.

___

AP Business Writer Pamela Sampson in Bangkok and Associated Press video journalist Jeffrey Schaeffer in Paris contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/eurobiz/*http%3A//news.yahoo.com/s/ap/20111027/ap_on_bi_ge/world_markets

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Human brains are made of the same stuff, despite DNA differences

ScienceDaily (Oct. 26, 2011) ? Despite vast differences in the genetic code across individuals and ethnicities, the human brain shows a "consistent molecular architecture," say researchers supported by the National Institutes of Health. The finding is from a pair of studies that have created databases revealing when and where genes turn on and off in multiple brain regions through development.

"Our study shows how 650,000 common genetic variations that make each of us a unique person may influence the ebb and flow of 24,000 genes in the most distinctly human part of our brain as we grow and age," explained Joel Kleinman, M.D., Ph.D., of the National Institute of Mental Health (NIMH) Clinical Brain Disorders Branch.

Kleinman and NIMH grantee Nenad Sestan, M.D., Ph.D. of Yale University, New Haven, Conn., led the sister studies in the Oct. 27, 2011 issue of the journal Nature.

"Having at our fingertips detailed information about when and where specific gene products are expressed in the brain brings new hope for understanding how this process can go awry in schizophrenia, autism and other brain disorders," said NIMH Director Thomas R. Insel, M.D.

Both studies measured messenger RNAs or transcripts. These intermediate products carry the message from DNA, the genetic blueprint, to create proteins and differentiated brain tissue. Each gene can make several transcripts, which are expressed in patterns influenced by a subset of the approximately 1.5 million DNA variations unique to each of us. This unique set of transcripts is called our transcriptome -- a molecular signature that is unique to every individual. The transcriptome is a measure of the diverse functional potential that exists in the brain.

Both studies found that rapid gene expression during fetal development abruptly switches to much slower rates after birth that gradually decline and eventually level off in middle age. These rates surge again as the brain ages in the last decades, mirroring rates seen in childhood and adolescence, according to one of the studies. The databases hold secrets to how the brain's ever-changing messenger chemical systems, cells and development processes are related to gene expression patterns through development.

For example, if a particular version of a gene is implicated in a disorder, the new resources might reveal how that variation affects the gene's expression over time and by brain region. By identifying even distant genes that may be turning on and off in-sync, the databases may help researchers discover whole modules of genes involved in the illness. They can also reveal how variation in one gene influences another's expression.

Prefrontal cortex

Kleinman's team focused on how genetic variations are linked to the expression of transcripts in the brain's prefrontal cortex, the area that controls insight, planning and judgment, across the lifespan. They studied 269 postmortem, healthy human brains, ranging in age from two weeks after conception to 80 years old, using 49,000 genetic probes. The database on prefrontal cortex gene expression alone totals more than 1 trillion pieces of information, according to Kleinman.

Among key findings in the prefrontal cortex:

  • Individual genetic variations are profoundly linked to expression patterns. The most similarity across individuals is detected early in development and again as we approach the end of life.
  • Different types of related genes are expressed during prenatal development, infancy, and childhood, so that each of these stages shows a relatively distinct transcriptional identity. Three-fourths of genes reverse their direction of expression after birth, with most switching from on to off.
  • Expression of genes involved in cell division declines prenatally and in infancy, while expression of genes important for making synapses, or connections between brain cells, increases. In contrast, genes required for neuronal projections decline after birth -- likely as unused connections are pruned.
  • By the time we reach our 50s, overall gene expression begins to increase, mirroring the sharp reversal of fetal expression changes that occur in infancy.
  • Genetic variation in the genome as a whole showed no effect on variation in the transcriptome as a whole, despite how genetically distant individuals might be. Hence, human cortexes have a consistent molecular architecture, despite our diversity.

In previous studies, Kleinman and colleagues have found that all genetic variations implicated to date in schizophrenia are associated with transcripts that are preferentially expressed in the fetal brain. This adds to evidence that the disorder originates in prenatal development. By contrast, he and his colleagues are examining evidence that genetic variation implicated in affective disorders may be associated with transcripts expressed later in life. They are also extending their database to include all transcripts of all the genes in the human genome, examining 1000 post-mortem brains, including many of people who had schizophrenia or other brain disorders.

Multiple brain regions

Sestan and colleagues characterized gene expression in 16 brain regions, including 11 areas of the neocortex, from both hemispheres of 57 human brains that spanned from 40 days post-conception to 82 years -- analyzing the transcriptomes of 1,340 samples. Using 1.4 million probes, the researchers measured the expression of exons, which combine to form a gene's protein product. This allowed them to pinpoint changes in these combinations that make up a protein, as well as to chart the gene's overall expression.

Among key findings:

  • Over 90 percent of the genes expressed in the brain are differentially regulated across brain regions and/or over developmental time periods. There are also widespread differences across region and time periods in the combination of a gene's exons that are expressed.
  • Timing and location are far more influential in regulating gene expression than gender, ethnicity or individual variation.
  • Among 29 modules of co-expressed genes identified, each had distinct expression patterns and represented different biological processes. Genetic variation in some of the most well-connected genes in these modules, called hub genes, has previously been linked to mental disorders, including schizophrenia and depression.
  • Telltale similarities in expression profiles with genes previously implicated in schizophrenia and autism are providing leads to discovery of other genes potentially involved in those disorders.
  • Sex differences in the risk for certain mental disorders may be traceable to transcriptional mechanisms. More than three-fourths of 159 genes expressed differentially between the sexes were male-biased, most prenatally. Some genes found to have such sex-biased expression had previously been associated with disorders that affect males more than females, such as schizophrenia, Williams syndrome, and autism.

The Sestan study was also funded by NIH's National Institute on Child Health and Human Development, National Institute on Neurological Disorders and Stroke, and National Institute on Drug Abuse. Data for the Sestan study are posted at www.humanbraintranscriptome.org and at http://www.developinghumanbrain.org, as part of a larger ongoing study, BrainSpan, funded by NIMH under the American Recovery and Reinvestment Act to create an Atlas of Human Brain Development.

The Kleinman study data on genetic variability are accessible to qualified researchers at http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id5phs000417.v1.p1, while the gene expression data can be found at http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc5GSE30272. In addition, BrainCloud, a web browser application developed by NIMH to interrogate the Kleinman study data, can be downloaded at http://www.libd.org/braincloud.

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The above story is reprinted from materials provided by NIH/National Institute of Mental Health.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal References:

  1. Hyo Jung Kang, Yuka Imamura Kawasawa, Feng Cheng, Ying Zhu, Xuming Xu, Mingfeng Li, Andr? M. M. Sousa, Mihovil Pletikos, Kyle A. Meyer, Goran Sedmak, Tobias Guennel, Yurae Shin, Matthew B. Johnson, ?eljka Krsnik, Simone Mayer, Sofia Fertuzinhos, Sheila Umlauf, Steven N. Lisgo, Alexander Vortmeyer, Daniel R. Weinberger, Shrikant Mane, Thomas M. Hyde, Anita Huttner, Mark Reimers, Joel E. Kleinman, Nenad ?estan. Spatio-temporal transcriptome of the human brain. Nature, 2011; 478 (7370): 483 DOI: 10.1038/nature10523
  2. Carlo Colantuoni, Barbara K. Lipska, Tianzhang Ye, Thomas M. Hyde, Ran Tao, Jeffrey T. Leek, Elizabeth A. Colantuoni, Abdel G. Elkahloun, Mary M. Herman, Daniel R. Weinberger, Joel E. Kleinman. Temporal dynamics and genetic control of transcription in the human prefrontal cortex. Nature, 2011; 478 (7370): 519 DOI: 10.1038/nature10524

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2011/10/111026143719.htm

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শুক্রবার, ২৮ অক্টোবর, ২০১১

Hybrid Air Vehicles Make Gains On Traditional Airplanes

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Hybrid Air Vehicles Make Gains On Traditional Airplanes
Seventy-four years after the zeppelin, another gas giant arises.Hybrid Air Vehicles' new aircraft is not technically a blimp. Nor is it a zeppelin, a craft that saw its end with the Hindenburg explosion in 1937 (and a rebirth, of sorts, in the proto-heavy-metal band's name).

Source: FastCompany
Posted on: Friday, Oct 28, 2011, 7:28am
Views: 21

Source: http://www.labspaces.net/114738/Hybrid_Air_Vehicles_Make_Gains_On_Traditional_Airplanes

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Expert says Jackson likely addicted to pain med (AP)

LOS ANGELES ? Lawyers for Michael Jackson's doctor sought to shift blame Thursday to another doctor and a drug different from the anesthetic that killed the star, calling an expert to testify that Jackson was addicted to Demerol in the months before his death.

They suggested the singer's withdrawal from the painkiller triggered the insomnia that Dr. Conrad Murray was trying to resolve when he gave Jackson the anesthetic propofol.

Murray's attorneys claim Jackson self-administered a fatal dose of propofol as a sleep aid.

Authorities contend Murray delivered the lethal dose and botched resuscitation efforts. Murray has pleaded not guilty to involuntary manslaughter in Jackson's June 2009 death.

There was no mention of propofol during the testimony of Dr. Robert Waldman, an addiction expert who said he studied the records of Dr. Arnold Klein, Jackson's longtime dermatologist, in concluding the star developed a dependency on the powerful painkiller. Records showed Klein used Demerol on Jackson repeatedly for procedures to enhance his appearance.

No Demerol was discovered in the singer's system when he died, but propofol was found throughout his body.

Waldman relied on Klein's records from March 2009 until days before Jackson died. Waldman said he was not shown records for earlier periods and didn't review a police interview of Murray about his treatment of the star.

Under questioning by Murray's lead lawyer, Ed Chernoff, Waldman said: "I believe there is evidence that he (Jackson) was dependent on Demerol, possibly."

Klein has emerged as the missing link in the involuntary manslaughter trial, with the defense raising his name at every turn and the judge ruling he may not be called as a witness because his care of Jackson is not at issue. He has not been charged with any wrongdoing.

But Klein's handwritten notes on his visits with Jackson were introduced through Waldman, who said Klein was giving Jackson unusually high doses of Demerol for four months ? from March through June, 2009 ? with the last shots coming three days before the singer's death.

Over three days in April, the records showed Jackson received 775 milligrams of Demerol along with small doses of the sedative Versed. Waldman's testimony showed Klein, who also was Jackson's longtime friend, was giving the singer huge doses of the powerful drug at the same time Murray was giving Jackson the anesthetic propofol to sleep.

"This is a large dose for an opioid for a dermatology procedure in an office," Waldman said.

He told jurors the escalating doses showed Jackson had developed a tolerance to the drug and was probably addicted. He said a withdrawal symptom from the drug is insomnia.

On cross-examination, prosecutor David Walgren tangled with the expert, who was hostile to most of his questions. He elicited from Waldman that the law requires physicians to keep accurate and detailed records, which Murray did not. The doctor also said all drugs should be kept in a locked cabinet or safe where they could not be stolen or diverted by anyone.

Waldman said every doctor also must document when the drugs are stored and when they are used. Murray told police he kept no records on his treatment of Jackson.

Waldman, who has treated celebrities and sports stars at expensive rehab clinics, told jurors treatment can work if the addict is willing to admit a problem.

Several prosecution experts have said the propofol self-administration defense was improbable, and a key expert said he ruled it out completely, arguing the more likely scenario was that Murray gave Jackson a much higher dose than he has acknowledged.

Jackson had complained of insomnia as he prepared for a series of comeback concerts and was receiving the anesthetic and sedatives from Murray, his personal physician, to help him sleep.

Murray's police interview indicates he didn't know Jackson was being treated by Klein and was receiving other drugs.

In response to questions from a prosecutor, Waldman said some of the symptoms of Demerol withdrawal were the same as those seen in patients withdrawing from the sedatives lorazepam and diazepam. Murray had been giving Jackson both drugs.

The final defense witness was to be Dr. Paul White, a propofol expert.

White and Waldman do not necessarily have to convince jurors that Jackson gave himself the fatal dose, but merely provide them with enough reasonable doubt about the prosecution's case against Murray.

___

AP Entertainment Writer Anthony McCartney contributed to this report.

___

McCartney can be reached at http://twitter.com/mccartneyAP

Source: http://us.rd.yahoo.com/dailynews/rss/crime/*http%3A//news.yahoo.com/s/ap/20111027/ap_en_mu/us_michael_jackson_doctor

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Intriguing 'In Time' gets old fast

It's refreshing to see a low-tech major studio science fiction film in this day and age, one in which the only physical manifestation of its futuristic setting is a glowing digital clock emblazened on everyone's lower arm that offers a running tally on how much time they've got to live. As novel and absorbing as "In Time" is in several respects, however, Andrew Niccol's latest conception of an altered but still recognizable future feels undernourished in other ways that are not as salutary, preventing the film from fulfilling its strong inherent promise. The imperiled-lovers-on-the-run action format with Justin Timberlake and Amanda Seyfried heading an insanely attractive cast should produce decent mid-range box office totals.

  1. Quick facts

    Starring: Amanda Seyfried, Justin Timberlake, Cillian Murphy, Vincent Kartheiser, Olivia Wilde, Matt Bomer, Johnny Galecki
    Director: Andrew Niccol
    Run time: 1 hour, 49 minutes
    MPAA rating: PG-13 for violence, some sexuality and partial nudity, and brief strong language

In fact, it is hard to think of another film with such a uniformly striking lineup of actors; when, in the opening minutes, you have to adjust to the fact that Olivia Wilde is playing Timberlake's mother, you know the casting is skewed in a very particular direction, one dictated by the story's very premise: At this unspecified moment in what in sure looks like, but is not identified as, Los Angeles, the aging process stops at 25. Giving new currency to the quote attributed to Benjamin Franklin, ?Time is money? has literally become the motto of the society. Rather than striving for financial gain, personal ambition is directed entirely at acquiring more time; the ?rich? have stored up thousands, even millions of years, while the poor work, borrow or steal to get enough just to make it to tomorrow. But when your arm clock ticks down to zero, you're a goner.

Story: Timberlake: I stole a golf cart with Ryan Gosling

The specifics of this are inevitably intriguing; a phone call costs you a minute of your life, breakfast in a fancy restaurant runs eight-and-a-half weeks. You can trade time with others just by locking arms but can be robbed the same way. At the outset, ghetto-dwelling Will Salas (Timberlake) is the inadvertent beneficiary of this exchange system. Popping into a bar where the clientele look like models for a mixed photo shoot for Maxim and GQ, Will is eventually bestowed with 100 years by a world-weary 105-year-old (Matt Bomer) who sums up the societal inequity of the system by observing that, ?For a few to be immortal, many must die.?

Slideshow: Justin Timberlake (on this page)

Devastated at his inability to save his mother with his newfound riches, fueled by the old man's weighty parting admonition ? ?Don't waste my time? ? and concerned that having so much time on his arm has made him a marked man, Will escapes from so-called Dayton (downtown L.A. by the concrete river) and makes his way to New Greenwich (Century City to the rest of us), where he shortly ends up in a casino playing for time opposite Philippe Weis (Vincent Kartheiser), whose holdings can only be measured in eons; so completely is time on the side of the wealthy that they have truly become the idle rich. Will also eyes Weis' daughter Sylvia (Seyfried), a spoiled girl constantly surrounded by bodyguards who just might possess a hitherto unstirred rebellious streak.

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Before long, Niccol morphs "In Time" into a yarn that borrows liberally from "Robin Hood" and "Bonnie and Clyde" as Will and Sylvia race around determined to steal from the rich and give to the poor. They are pursued not only by ?timekeeper? cop Leon (Cillian Murphy), who's spent years enforcing the system while, pointedly, staying alive only on a per diem, but by the menacing ?Minute Men? ? or, in another filmmaker's phrase, time bandits ?thieves led by a wacko (Alex Pettyfer) who enjoys draining his victims of their last remaining seconds.

Story: Justin Timberlake stops aging 'In Time'

The film's themes presciently merge with the ?haves/have-nots? disparities behind the current Wall Street occupation and related protests, and the desperate couple-against-the-world set-up has an enduring appeal. Unfortunately, as the film moves along, its brisk pace notwithstanding, too many issues come to weigh against it. As cleverly conceived as it is, the time-for-money substitution leaves a lot of questions unanswered. Other than for Leon and a few flunkies, there are no authority figures visible or alluded to. Who runs the country, the city? Is the rest of the world like this? How did the aging process get halted? Given so remarkable an achievement, why are there no other comparable technological advances? Why are all the cars customized early 1960s Lincoln Continentals, Jags and Cadillacs?

Story: Olivia Wilde finalizes divorce from Italian prince

Speaking of the 1960s, one of the film's most arresting touches it to give Seyfried face-framing hair that's straight Anna Karina/Brigitte Bardot/Elsa Martinelli circa 1963. It's a great look for Seyfried, who gets to pout a lot early on before joining forces with the boy from the other side of town. All the same, the couple doesn't generate much heat, which speaks to a greater shortcoming: As it centers on lovers who throw all caution to the wind to live intensely for a time on behalf of a cause greater than themselves, the story desperately needed to be told with urgency in a free-wheeling, vital, lyrical style with a fatalistic overlay, something achieved in films such as"Bonnie and Clyde," "Pierrot le fou" and "Thelma and Louise," for starters. Niccol's approach is too grounded and prosaic for such a spirit to take hold either with the camera or the actors, who run a lot but never together in a way that conveys their resolute connection. A more exalted, even delirious musical score would also have raised the stakes.

Timberlake capably carries the film but a glint of true rebelliousness, of a slightly unhinged element in his character's makeup, could have nudged the performance to another level. Seyfried, too, would have benefited from being further pushed. That everyone looks terrific is part of the point, but Murphy is able to provide a welcome suggestion that his character has seen it all and is wearing down, while Kartheiser's baby-faced visage and amused smile supply an extra layer of delight.

Working within the tight conceptual frame, ace cinematographer Roger Deakins enhances the real Los Angeles locations (including the CAA office building, which serves as Kartheiser's headquarters) as well as the creations of production designer Alex McDowell and costume designer Colleen Atwood.

Copyright 2011 The Hollywood Reporter

Source: http://today.msnbc.msn.com/id/45058624/ns/today-entertainment/

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Gaddafi body handed to NTC loyalists for burial (Reuters)

TRIPOLI (Reuters) ? Two loyalists of Libya's interim government were handed Muammar Gaddafi's body to bury secretly deep in the Sahara desert on Tuesday after a cleric prayed over his decomposing corpse, a Libyan official said.

With their Western allies uneasy that Gaddafi was roughed up and shot after his capture on Thursday, NTC forces had put his body on show in a cold store while they argued over what to do with it until its decay forced them to shut the doors on Monday.

"The process leading to his burial is taking place now," NTC official Abdel Majid Mlegta told Reuters by telephone. "Only two trusted people were assigned to this secret mission. These are not guards, but very trusted NTC people."

Other NTC officials said Gaddafi had already been buried, but Mlegta said the reports were premature. "Trust me, it takes time, and the burial will take place far from the media."

Final Muslim prayers were said over the bodies of the former leader and his son Mo'tassim by Gaddafi's personal cleric Khaled Tantoush, who was arrested with him, before they were removed from the Misrata compound where they had been on display.

The rites were also attended by two of Gaddafi's cousins, Mansour Dhao Ibrahim, once leader of the feared People's Guard, and Ahmed Ibrahim, who were both captured with Gaddafi after their convoy was attacked in a NATO air strike near Sirte, Gaddafi's home town, just after it had fallen.

"The NTC officials were handed the body after the sheikh completed the early morning ceremony and are taking him somewhere very far away into the desert," Mlegta said.

The killing of the 69-year-old in Sirte ended eight months of war, finally ending a nervous two-month hiatus since the NTC's motley forces overran the capital Tripoli.

But it also threatened to lay bare the regional and tribal rivalries that present the NTC with its biggest challenge.

NTC officials had said negotiations were going on with Gaddafi's tribal kinsmen from Sirte and within the interim leadership over where and how to dispose of the bodies, and on what the Misrata leaders in possession of the corpses might receive in return for cooperation.

"No agreement was reached for his tribe to take him," another NTC official told Reuters.

With the decay of the body forcing the NTC leadership's hand, it appeared to have decided that an anonymous grave would at least ensure the plot did not become a shrine.

An NTC official told Reuters several days ago that there would be only four witnesses to the burial, and all would swear on the Koran never to reveal the location.

NTC fears that Gaddafi's sons might mount an insurgency have been largely allayed by the deaths of two of those who wielded the most power, military commander Khamis and Mo'tassim, the former national security adviser.

Mo'tassim was captured along with his father in Sirte and killed in similarly unclear circumstances. Khamis was killed in fighting earlier in the civil war.

SAIF AL-ISLAM "NEAR BORDER"

An NTC official said Gaddafi's long-time heir-apparent Saif al-Islam was in the remote southern desert and set to flee Libya, with the NTC powerless to stop him.

"He's on the triangle of Niger and Algeria. He's south of Ghat, the Ghat area. He was given a false Libyan passport from the area of Murzuq," the official added.

He said Muammar Gaddafi's former intelligence chief Abdullah al-Senussi who, like Saif al-Islam, is wanted by the International Criminal Court, was involved in the matter.

"The region is very, very difficult to monitor and encircle," the official said. "The region is a desert region and it has ... many, many exit routes."

The death of the fallen strongman allowed the NTC to touch off mass rejoicing by declaring Libya's long-awaited "liberation" on Sunday in Benghazi, the seat of the revolt.

But it also highlighted a lack of central control over disparate armed groups, and the jockeying for power among local commanders as negotiations begin in earnest to form an interim government that can run free elections.

"Leaders from different regions, cities, want to negotiate over everything -- posts in government, budgets for cities, dissolving militias," said one senior NTC official in Tripoli, though he defended this as a healthy expression of freedom.

"Is that not democracy?" he asked. "It would be unusual if they did not (negotiate) after Muammar favored only a few places for 40 years. There is no reason why it cannot be peaceful."

Until the public was finally denied access to Gaddafi's body on Monday, fighters were still ushering sightseers into the chilled room where the bodies of Gaddafi, his son Mo'tassim and his former army chief lay, their flesh darkening and leaking fluids.

INVESTIGATION

The killings near Sirte, after mobile phone video footage was taken showing the captive Gaddafi being beaten and mocked by fighters apparently from Misrata, are also a matter of controversy -- at least outside Libya. The United Nations human rights arm has joined the Gaddafi family in seeking an inquiry.

NTC chairman Mustafa Abdel Jalil told a news conference on Monday that the NTC had formed a committee to investigate.

He also indicated that the interim authorities still held to an official line that Gaddafi may have been killed in "crossfire" with his own men, a view many NTC officials themselves seem ready to discount.

"Those who have an interest in killing him before prosecuting him are those who had an active role with him," said Abdel Jalil, who like many of the new leadership held positions of authority under Gaddafi.

Adding to concerns about Libya turning over a new leaf on respect for individuals, New York-based Human Rights Watch called on the NTC to probe an "apparent mass execution" of 53 people, apparently Gaddafi supporters, whom it found dead, some with their hands bound, at a hotel in Sirte.

Few Libyans seem troubled either about how Gaddafi and his entourage were killed or why their corpses were displayed for so long in what seemed a grim parody of the lying-in-state often reserved for national leaders.

"God made the pharaoh as an example to the others," said Salem Shaka, who was viewing the bodies in Misrata on Monday.

"If he had been a good man, we would have buried him. But he chose this destiny for himself."

(Reporting by Taha Zargoun in Sirte, Barry Malone and Jessica Donati in Tripoli, Rania El Gamal and Tim Gaynor in Misrata, Christian Lowe, Jon Hemming and Andrew Hammond in Tunis, Hamid Ould Ahmed in Algiers, Samia Nakhoul in Dubai and Matt Falloon in London; Editing by Alistair Lyon; Alastair Macdonald and Kevin Liffey; Editing by Mark Heinrich)

Source: http://us.rd.yahoo.com/dailynews/rss/world/*http%3A//news.yahoo.com/s/nm/20111025/wl_nm/us_libya

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বৃহস্পতিবার, ২৭ অক্টোবর, ২০১১

Michael Jackson Doctor Brought To Tears By Former Patients' Testimony

Conrad Murray's defense team presented a series of character witnesses who praised his skills as a physician.
By Gil Kaufman


Dr. Conrad Murray appears in court Wednesday
Photo: Getty Images

The day after one of Michael Jackson's former nurses was brought to tears while testifying at the involuntary manslaughter trial of the singer's former doctor, Conrad Murray, it was the cardiologist who got weepy on Wednesday (October 26) as his defense team produced a series of witnesses attesting to Murray's skills as a physician.

The Witnesses
» Andrew Guest, former patient of Conrad Murray
» Gerry Causey, former patient
» Lunette Sampson, former patient
» Ruby Mosley, former patient

Key Testimony
» After weeks of prosecution witnesses hammering away at what they deemed Murray's unprofessional, sloppy work in the final, crucial hours of MJ's life, the cardiologist's defense team spent Wednesday serving up a string of character witnesses to speak on Murray's behalf, according to the Los Angeles Times. The patients from Murray's Las Vegas and Houston practices talked about the hours he spent speaking to them, calling them at home and on weekends, and the free services he offered to those who were indigent. "That man sitting there is the best doctor I've ever seen," said Andrew Guest, who Murray treated for a heart condition in 2002. "I'm alive because of that man." Their testimony caused Murray to well up with tears at various points.

» Longtime patient and friend Causey said his appointments with Murray often lasted more than four hours, with the doctor often calling Causey's wife afterward to explain his treatment. Sampson also testified to Murray's careful, exhaustive attention and Mosley said Murray set up a clinic in a low-income neighborhood in honor of his father, who was a physician in that area.

» While cross-examining the witnesses, prosecutor David Walgren pointed out that each patient had received care for heart-related ailments and were not treated for sleep disorders or drug dependency. Prosecutors have said Murray's motivation to give Jackson the surgical anesthetic propofol was his promised six-figure monthly salary.

» Each patient also noted that when Murray did sedate them it was in a hospital setting with monitoring equipment and backup personnel. Prosecutors have argued that Murray did not have proper monitoring equipment or a nurse assistant when he gave Jackson a fatal dose of propofol and then left the room on June 25, 2009.

» When jurors left for the day, Superior Court Judge Michael Pastor spoke directly to Murray and reminded him that he has a right to choose whether or not he testifies on his own behalf in the trial. Pastor said he would ask Murray for an answer on that question later this week when the defense rests its case. Murray was not listed on Thursday's defense witness roster submitted by attorney Ed Chernoff.

Murray, who was being paid $150,000 a month to care for Jackson, has pleaded not guilty to the felony charge of involuntary manslaughter and is now facing four years in prison. But new sentencing laws in California aimed at mandatorily reducing state prison overcrowding mean that, as a nonviolent offender with no prior record, he could be sentenced to county jail instead. If that is the case, his sentence could be reduced to two years and, because of overcrowding in the Los Angeles County jail, he may be allowed to serve the majority of his time under supervised house arrest.

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Source: http://www.mtv.com/news/articles/1673244/michael-jackson-trial-conrad-murray-patients.jhtml

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BlackBerry Bold 9790 Caught On Film Ahead Of Dubai Debut?

bb9790RIM may be pinning their hopes on BBX, but that doesn't mean they're done churning out classic BlackBerrys. Case in point: the revamped Bold 9790 has been revealed in a new set of photos that doesn't look like someone took them during an earthquake.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/6fviabsn4oQ/

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S.978: What Justin Bieber has to do with online streaming bill

S.978 is the latest chapter in the fight to protect major content providers, including the movie industry, which say they lose millions of dollars yearly from illegal streams on sites like YouTube.

Is Justin Bieber facing hard time behind bars?

Skip to next paragraph

The teen star?s fate is up for debate, not in grade school cafeterias and strip malls, but in the US House of Representatives Wednesday, where lawmakers are expected to take up a bill that would punish the unauthorized online streaming of copyrighted content.

The proposed bill, titled the Commercial Felony Streaming Act, or S.978, is the latest chapter in the ongoing fight to protect major content providers including the motion-picture, recording, and television industries, which say they lose millions of dollars each year from illegal online video and audio streams on sites like YouTube.

Before his multiplatinum record sales, Mr. Bieber first gained notice as an online sensation, uploading videos of his interpretations of the pop hits of the day. Supporters say this makes him vulnerable to prosecution if the bill becomes law.

Technology advocacy organizations, such as Fight for the Future, say that the bill is too expansive and would criminalize what they categorize as harmless activities, such as videos of people ?singing a song, dancing to background music, or posting videos of a kid?s school play.?

To make its point, Fight for the Future says Bieber would be facing five years in prison if the bill had been law when he made his first videos in his bedroom. An online petition is circulating via FreeBieber.org, a website the organization branded for its cause.

Lawmakers, however, say that the legislation is not intended to clamp down on fans, citing one basic fact: Uploading videos (which is what many people do) is not the same thing as streaming (some of which the bill would regulate). They also say the bill is only meant to address commercial bootleggers, who are intentionally and willfully distributing content for financial gain.

?This bill does not criminalize uploading videos to YouTube or streaming videos at home,? says Linden Zakula, communications director for Sen. Amy Klobuchar (D) of Minnesota, a co-sponsor of the bill along with Sens. Chris Coons (D) of Delaware and John Cornyn (R) of Texas.

Kevin Thompson, an Internet law and copyright attorney in Chicago, agrees that the bill?s language is intended to stop operators from hosting illegal streams of content that have a high price tag ? such as movies, sports games, or concerts.

But, Mr. Thompson says, free-technology advocates have reason to worry because the bill?s broad language has ?potential for misuse.?

?You could read it in such a way a prosecutor could decide that they could stretch it enough to make a case? to go after an individual suspected of piracy, he says.

The fight over this bill is part of a long line of strategies by media giants to protect their content from being infringed by online pirates.

The Digital Millennium Copyright Act, a federal law enacted in 1998, put copyright owners, not service providers, in charge of policing the Internet for pirated content. The result: Up to now, media companies have been able to issue takedown requests to sites such as YouTube only when they notice piracy. The sheer volume of videos uploaded to the site each day ? 48 hours of video each minute, according to the company ? has driven media companies to push for more regulation.

One example: In July, the Recording Industry Association of America (RIAA), which represents the major music companies, requested a subpoena to find out the IP address, among other information, of a YouTube user who illegally uploaded footage of a Britney Spears concert. The RIAA sought a similar subpoena to pursue users of Box.net, an online site that promotes content sharing, on the grounds they were illegally pirating content before its official release.

The RIAA, as well as the Motion Picture Association of America, Sony Pictures Entertainment, Viacom, NBCUniversal, Time Warner, and many other media giants and advocacy organizations representing the entertainment and sports industries are supporting the bill.

Those parties continue to protest a landmark 2010 federal court decision that found YouTube and its parent company, Google, not liable under federal copyright law for users who may be illegally sharing copyrighted content owned by Viacom. Viacom, which sought $1 billion in damages, returned to a New York court last week for an appeals hearing. The three-judge panel has not yet released its decision.

The bill up for debate in the House this week is not unexpected, says Corynne McSherry, intellectual property director at the Electronic Frontier Foundation, a nonprofit digital-rights advocacy group based in San Francisco that is opposed to the legislation.

?Big media is losing in the civil courts so they said, ?OK, we can?t win there because the law is not favoring us. So we?re going to go to Washington and see if we can win there, either by getting government to do the work for us or to pass legislation to give us new powers we didn?t have before,? ? Ms. McSherry says.

?The reality is, a certain amount of infringement online is going to happen,? she says.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/YOXxomwIYJw/S.978-What-Justin-Bieber-has-to-do-with-online-streaming-bill

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বুধবার, ২৬ অক্টোবর, ২০১১

German satellite crashed over Asia's Bay of Bengal

BERLIN (AP) ? Heavily populated Asian cities avoided a dangerous collision with space junk last weekend as a defunct German satellite crashed into the sea somewhere between India and Myanmar.

The ROSAT satellite re-entered the atmosphere at 0150 GMT Sunday (9:50 p.m. Saturday EDT) above South Asia's Bay of Bengal, but it remains unclear how much, if any, of its debris actually reached the sea's surface, the German Aerospace Center said Tuesday.

Most of the 21-year-old satellite was expected to burn up as it hit the atmosphere, but up to 30 fragments weighing a total of 1.87 tons (1.7 metric tons) may have splashed into the sea.

Scientists could no longer communicate with the defunct satellite, let alone control it.

Two Chinese cities with millions of residents each, Chongqing and Chengdu, were only minutes further northeast along the satellite's projected path, according to Jonathan McDowell of the Harvard-Smithsonian Center for Astrophysics in Cambridge, Massachusetts.

The 2.69-ton (2.4 metric ton) scientific ROSAT satellite was launched in Cape Canaveral, Florida, in 1990 and retired in 1999 after being used for research on black holes and neutron stars.

A dead NASA satellite fell into the southern Pacific Ocean last month, causing no damage but spreading debris over a 500-mile (800-kilometer) area.

Since 1991, space agencies have adopted new procedures to lessen space junk. NASA says it has no more large satellites that will fall back to Earth uncontrolled in the next 25 years.

___

Online:

The German space agency on ROSAT: http://tinyurl.com/645k8hj

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/b2f0ca3a594644ee9e50a8ec4ce2d6de/Article_2011-10-25-Falling-Satellite/id-4ab0c63041e74239805360aec98af0c2

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